Zinc must be present in the oil for solid lifter cams or the cam lobes will be worn away. This is true for any engine running a solid lifter cam.
The Cleveland engines have a higher load on the lifters due to the angles created by the canted valve arrangement. As such it is a good practice to use a oil with zinc in ANY Cleveland engine.
High zinc content will destroy catalytic converters though, so use in engines after 74 is problematic.
As to the lead substitute additive, it should be used for track events, and if you are planning to drive your car aggressively. Cleveland heads do not have a lot of room for hardened seats and usually the 4 V heads, when rebuilt don't get hardened seats unless someone is insistent, as cutting into the water jacket is a bad thing.
For street driving, I don't see it as necessary, though it won't hurt anything.
Cleveland engines have several potential weak points that can be addressed in an overhaul or rebuild.
The stock rods are great, but the nuts on the rod bolts are not great quality and have been known to pull off at high RPM ARP nuts can be added to eliminate this or you can go ahead and use their bolts as well.
The Stock valves are two piece and likewise at high RPM the head of the valv can separate and destroy the engine. If the heads are off replace two piece intake valves with one piece units.
You can identify the two piece valves without removing the heads using a mechanic's scope and looking through the spark plug hole at the underside of the intake valve (depending on carbon build up). If it says ford in an oval-it is a two piece unit in all likelyhood.
Until these items have been addressed RPM's should be limited to under 5500-6000 depending on your risk aversion.