The difference between all the gears, is that the higher the number, the more cogs the gear will have. In other words, a 4.10 will have more cogs than a 3.73. The more cogs you have, the faster your rear end will spin, making your rear tires spin faster. But, you reach a point of no return at high speeds. Higher gear ratios are for stop light to stop light or drag racing. Gear ratios that are like 2.80:1 are for highway speeds and cruising. The lower the ratio, the better the gas mileage on the freeway because the engine RPM is lower.